Orexin drives arousal, motivation, and reward-seeking. Understanding this brain system may help explain motivation, addiction ...
When humans and other animals move through familiar or unfamiliar environments, their brains rely on numerous intricate ...
Scientists have long been fascinated by two promising classes of antibiotics that disable RNA polymerase (RNAP). They knew that these drugs could grind gene expression to a halt in several pathogens, ...
The cell membrane is a fundamental biological structure. These lipid layers surround and organize every cell, controlling ...
Research reveals the role of orexin neurons in maintaining motivation, with implications for the treatment of ADHD, depression and addiction.
“A fever is a coping response, not a sign of illness.” —George Vaillant Like all living systems, we human beings have evolved multiple mechanisms for defending against threats to our survival and ...
Scientists at The Wistar Institute have identified a new mechanism behind the chemotherapy resistance that makes ovarian cancer so lethal. In a new study published in The Journal for ImmunoTherapy of ...
As recognition of the microbiome's role in health and disease continues to grow, attention is shifting from identifying which microbes are present in an individual's microbiome to understanding how ...
Mechanosensitive Piezo ion channels, particularly Piezo1 and Piezo2, are gaining recognition as central regulators of digestive system physiology and disease.